Actively Recruiting
Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
Led by Sanford Health · Updated on 2026-02-10
148
Participants Needed
1
Research Sites
478 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to look at pain management with opioids versus non-opioids after knee arthroscopy. This study will determine 1) whether the most commonly used non-narcotic medications provide pain relief comparable with the most commonly prescribed narcotic medications in patients undergoing arthroscopic knee surgery, and 2) whether patients' characteristics (gender, pre-operative knee symptoms, workers compensation status and employment status) affect pain level following surgery or medication usage.
CONDITIONS
Official Title
Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years
- Undergoing elective arthroscopic knee surgery including partial meniscectomy, chondroplasty, or loose body removal
You will not qualify if you...
- Previously enrolled in this study for the other knee
- Scheduled for knee ligament reconstruction surgery
- Undergoing bilateral knee arthroscopy
- History of chronic opioid or long-term analgesic use
- Documented or suspected substance abuse
- Documented or suspected chronic pain syndrome
- Known allergy or contraindication to hydrocodone, acetaminophen, or ibuprofen
- Significant medical problems in the past year (arrhythmia, cardiovascular issues, gastrointestinal bleeding, liver or kidney disease)
- Active peptic ulcer disease or severe heartburn history
- Signs of infection at enrollment
- Pregnant or nursing
- Diagnosis of cognitive impairment
- Unable or unwilling to provide informed consent
- Inability to understand study requirements or refusal to consent
- Currently taking blood thinners (except low-dose aspirin)
- Other medical or psychological conditions preventing treatment or follow-up
- Alcoholism
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Sanford Health
Fargo, North Dakota, United States, 58122
Actively Recruiting
Research Team
A
Amy Tuchscherer
CONTACT
K
Katie Jensen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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