Actively Recruiting
Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies
Led by Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș" · Updated on 2026-01-12
200
Participants Needed
2
Research Sites
104 weeks
Total Duration
On this page
Sponsors
S
Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"
Lead Sponsor
I
Institutul Clinic Fundeni
Collaborating Sponsor
AI-Summary
What this Trial Is About
Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.
CONDITIONS
Official Title
Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients admitted into one of the specified wards of the involved hospitals
- Patients aged 18-60 years
- Suspected meningitis, encephalitis, stroke or cerebral tumors
You will not qualify if you...
- Age under 18 years or over 60 years old
- Ocular lesions preventing ocular ultrasound (palpebral infections, cornean erosions, glaucoma, trauma)
- Conditions preventing lumbar puncture (coagulation disorders, epidural abscesses, local infections)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Fundeni Clinical Institute
Bucharest, Bucharest, Romania, 022315
Actively Recruiting
2
"Dr. Victor Babeș" Clinical Hospital for Infectious and Tropical Diseases
Bucharest, Bucharest, Romania, 030303
Actively Recruiting
Research Team
B
Bogdan Pavel, MD, PhD, DESA
CONTACT
S
Sebastian Isac, MD, PhD, DESA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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