Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06797765

Optical Coherence Tomography Angiography in Neurological Disease

Led by University of Texas Southwestern Medical Center · Updated on 2025-11-19

50

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Optical Coherence Tomography Angiography (OCTA) is a non-invasive tool that images the neurovascular structures of the eye by using near-infrared light. Previous literature has demonstrated the potential of OCTA as a screening tool in stroke, but its utility in other neurological illness such as intracranial hemorrhage is unclear. Hence, this pilot study will gather preliminary data to support future grant applications to investigate this area more fully by recruiting patients with neurological illness and healthy controls and comparing their OCTA imaging parameters.

CONDITIONS

Official Title

Optical Coherence Tomography Angiography in Neurological Disease

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Patient admitted to the neuroscience intensive care unit with a diagnosis of: subarachnoid hemorrhage, intracerebral hemorrhage, intracranial aneurysm (ruptured or unruptured), intracranial vascular malformation, ischemic stroke, seizure disorder, intracranial infection, intracranial tumor(s), inflammatory demyelinating disease, traumatic brain injury and/or neuromuscular respiratory failure OR subjects from the community without major neurologic, cardiovascular, pulmonary or metabolic disease
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Non-English speaking
  • Glasgow Coma Scale motor score less than 6 (must be able to follow commands)
  • Temporary or permanent physical limitation that prevents sitting up and looking inside the OCTA device

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UT Southwestern Medical Center

Dallas, Texas, United States, 75235

Actively Recruiting

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Research Team

N

Noah Jouett, DO, PhD

CONTACT

E

Emily Melikman, MBBS, RN

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Optical Coherence Tomography Angiography in Neurological Disease | DecenTrialz