Actively Recruiting
Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease
Led by Johns Hopkins University · Updated on 2026-03-09
1050
Participants Needed
1
Research Sites
361 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
N
National Eye Institute (NEI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care treatment.
CONDITIONS
Official Title
Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 99 years
- Subjects either healthy or diagnosed with retinal vascular disease such as diabetic retinopathy, hypertension, retinal vein/arterial occlusion, or macular degeneration
- Willingness and ability to provide informed consent and cooperate with study procedures
- Undergoing or eligible for standard-of-care eye screening or treatment at clinical sites
You will not qualify if you...
- Younger than 18 years old
- Pregnant females
- Developmental delay
- Unable to provide informed consent
- Unable to cooperate with tests and study instructions
- Images with motion artifact or signal strength less than 7
- History of glaucoma
- History of age-related macular degeneration
- History of any visually significant eye disease
- History of proliferative diabetic retinopathy
- History of any inflammatory disease
- History of heart disease
- History of thyroid disease
- For healthy controls: history of any type of diabetes mellitus
- For healthy controls: history of any type of hypertension
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Wilmer Eye Institute
Baltimore, Maryland, United States, 21287
Actively Recruiting
Research Team
A
Amir H Kashani, MD, PhD
CONTACT
A
Ana C Martinez, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
4
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