Actively Recruiting

All Genders
NCT07293858

Optical Coherence Tomography: Prognostic Value and Artificial Intelligence

Led by Radboud University Medical Center · Updated on 2025-12-19

1000

Participants Needed

1

Research Sites

370 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the prognostic value of optical coherence tomography (OCT) imaging of the coronary arteries. OCT provides high-resolution images of the vessel wall and stented segments during routine cardiac catheterization. All patients who undergo OCT as part of their clinical care are invited to participate in this prospective registry. The study will examine whether specific OCT-derived characteristics-such as plaque morphology, vulnerable features, or indicators of stent optimization-are associated with long-term clinical outcomes. Follow-up information on symptoms, medication use, hospitalizations, cardiac procedures, and major cardiac events will be collected through medical records, questionnaires, and national registry data over a period of up to 10 years. In addition, pseudonymized OCT pullbacks will be used to support the development of an artificial intelligence (AI) algorithm for automated annotation of OCT images. This algorithm may help improve the clinical interpretation of OCT by identifying relevant imaging features in a consistent and efficient manner. Participation is voluntary and includes permission to use clinical data, OCT images, and follow-up information for research purposes. Data are coded to protect participant privacy and stored securely according to applicable regulations. The results of this study may contribute to better understanding of coronary plaque characteristics and may support improved decision-making in interventional cardiology.

CONDITIONS

Official Title

Optical Coherence Tomography: Prognostic Value and Artificial Intelligence

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All consecutive patients undergoing intracoronary OCT imaging at the Radboud University Medical Center or other participating centers
  • OCT performed according to current clinical guidelines at the treating physician's discretion
  • Written informed consent obtained after the OCT procedure
Not Eligible

You will not qualify if you...

  • Patients who decline or are unable to provide informed consent
  • Patients without valid contact details or for whom follow-up is not possible

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Radboudumc

Nijmegen, Gelderland, Netherlands, 6525GA

Actively Recruiting

Loading map...

Research Team

J

Joske L. van der Zande

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Optical Coherence Tomography: Prognostic Value and Artificial Intelligence | DecenTrialz