Actively Recruiting
Optical Coherence Tomography: Prognostic Value and Artificial Intelligence
Led by Radboud University Medical Center · Updated on 2025-12-19
1000
Participants Needed
1
Research Sites
370 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate the prognostic value of optical coherence tomography (OCT) imaging of the coronary arteries. OCT provides high-resolution images of the vessel wall and stented segments during routine cardiac catheterization. All patients who undergo OCT as part of their clinical care are invited to participate in this prospective registry. The study will examine whether specific OCT-derived characteristics-such as plaque morphology, vulnerable features, or indicators of stent optimization-are associated with long-term clinical outcomes. Follow-up information on symptoms, medication use, hospitalizations, cardiac procedures, and major cardiac events will be collected through medical records, questionnaires, and national registry data over a period of up to 10 years. In addition, pseudonymized OCT pullbacks will be used to support the development of an artificial intelligence (AI) algorithm for automated annotation of OCT images. This algorithm may help improve the clinical interpretation of OCT by identifying relevant imaging features in a consistent and efficient manner. Participation is voluntary and includes permission to use clinical data, OCT images, and follow-up information for research purposes. Data are coded to protect participant privacy and stored securely according to applicable regulations. The results of this study may contribute to better understanding of coronary plaque characteristics and may support improved decision-making in interventional cardiology.
CONDITIONS
Official Title
Optical Coherence Tomography: Prognostic Value and Artificial Intelligence
Who Can Participate
Eligibility Criteria
You may qualify if you...
- All consecutive patients undergoing intracoronary OCT imaging at the Radboud University Medical Center or other participating centers
- OCT performed according to current clinical guidelines at the treating physician's discretion
- Written informed consent obtained after the OCT procedure
You will not qualify if you...
- Patients who decline or are unable to provide informed consent
- Patients without valid contact details or for whom follow-up is not possible
AI-Screening
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Trial Site Locations
Total: 1 location
1
Radboudumc
Nijmegen, Gelderland, Netherlands, 6525GA
Actively Recruiting
Research Team
J
Joske L. van der Zande
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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