Actively Recruiting
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
Led by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Updated on 2025-09-18
48
Participants Needed
1
Research Sites
94 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery. This project is considered "Research" and participation is voluntary. Upon enrollment in this study, the research team will collect data from the patient's medical records. The patient will undergo all of the normal testing and procedures required pre-operatively (standard of care). The study team will then randomly assign the patient (like a flip of a coin) to one of three different study arms for pain management during surgery: 1. Laparoscopic Transversus Abdominis Plane Block (LapTAP) with Local Anesthetic (LA) 2. Laparoscopic Transversus Abdominis Plane Block (LapTAP) only 3. Local Anesthetic (LA) only The patient will receive standard pre- and post-operative care according to clinical guidelines (routine care). The study team will collect information from the patient's medical record for the first 24 hours after their surgery and upon discharge. This information will include pain scores, amount of medication required, any side effects the patient may have experienced, and satisfaction with pain control. Participation in the study will end upon discharge from the hospital.
CONDITIONS
Official Title
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female patients age 65 18 - 89
- Scheduled for elective hepatic, gastric, biliary, pancreatic, gynecologic, colorectal, or other gastrointestinal minimally invasive cancer surgery
- Provided informed consent to participate
- Have an ASA physical status classification of I, II, or III
- Undergoing procedures expected to last more than 1 hour and less than 8 hours
- Able to understand and self-report pain using the Visual Analog Scale
You will not qualify if you...
- Age less than 18 or 90 and older
- Pre-existing hepatic dysfunction or cirrhosis
- ASA classification of IV or higher
- Chronic pain disorders or long-term opioid or analgesic therapy
- Known allergies or contraindications to study drugs or procedures
- Cognitive or psychiatric conditions interfering with pain assessment or consent
- Unable to understand English for consent and study information
- Major surgery within the last 6 months
- Pregnant females
- Currently enrolled in another clinical trial that may affect outcomes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
AHN West Penn Hospital
Pittsburgh, Pennsylvania, United States, 15224
Actively Recruiting
Research Team
C
Casey Allen, MD
CONTACT
A
AHN Clinical Trials Contact
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here