Interfascial Plane Blocks and Laparoscopic Abdominal Surgery: A Narrative Review.
James Harvey Jones, Robin Aldwinckle
https://pubmed.ncbi.nlm.nih.gov/33122942Actively Recruiting
Led by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Updated on 2025-09-18
48
Participants Needed
1
Research Sites
26 weeks
Total Duration
Researchers are evaluating the effectiveness of three different routine pain management methods used during minimally invasive cancer surgery. This study compares Laparoscopic Transversus Abdominis Plane block (LapTAP) combined with Local Anesthetic (LA), LapTAP alone, and LA alone. The trial aims to improve postoperative pain control in patients undergoing various types of minimally invasive oncologic surgeries by assessing these methods in a prospective, randomized control trial. Participants will be randomly assigned to one of three groups: receiving LapTAP with LA, LapTAP alone, or LA alone during their surgery. The LapTAP procedure involves injecting ropivacaine into the fascial plane between abdominal muscles, while LA is administered around surgical port sites. All patients will receive standard pre- and post-operative care according to clinical guidelines, with the study treatments given during the surgery. During the study, researchers will collect data from medical records for 24 hours post-surgery and until hospital discharge, typically about one week. They will monitor pain scores hourly for 24 hours and at discharge, opioid consumption, recovery analgesic time, side effects, and patient satisfaction with pain management. Participation ends at hospital discharge, with no additional long-term follow-up beyond this period.
CONDITIONS
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Surgery duration plus up to 1 week post-surgery
Participants undergo minimally invasive oncologic surgery and receive one of three pain management interventions: Laparoscopic Transversus Abdominis Plane block with Local Anesthetic, LapTAP alone, or Local Anesthetic alone.
1 surgery visit and daily assessments up to hospital discharge (on average 1 week)
Duration - Up to 1 week post-surgery
Participants are monitored for pain control effectiveness, opioid consumption, adverse events, and patient satisfaction until hospital discharge, approximately 1 week after surgery.
Daily assessments during hospital stay until discharge
Total: 1 location
1
AHN West Penn Hospital
Pittsburgh, Pennsylvania, United States, 15224
Actively Recruiting
C
Casey Allen, MD
A
AHN Clinical Trials Contact
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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