Actively Recruiting
Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration.
Led by ART Fertility Clinics LLC · Updated on 2025-02-21
316
Participants Needed
2
Research Sites
118 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to compare the difference in clinical pregnancy, miscarriage and livebirth rate between day 6 euploid blastocyst transfer on the 6th and the 7th day of progesterone exposure in Hormonal Replacement Therapy (HRT) FET cycles. This prospective \& randomized study will only include euploid day 6 blastocysts. This will be the first prospective study of euploid day 6 blastocysts thereby excluding aneuploidy as a cause of miscarriage and implantation failure. The point of randomization will occur on the day of progesterone commencement.
CONDITIONS
Official Title
Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 18 years to 43 years
- Having at least 1 euploid cryopreserved day 6 blastocyst of at least Grade BB quality
- Endometrial trilaminar appearance on the day of progesterone start
You will not qualify if you...
- Uterine abnormality
- Hydrosalpinx
- Asherman syndrome
- Any known contraindications or allergy to oral estradiol or progesterone
- Spontaneous ovulation during HRT cycle
- Discontinuation of HRT medication
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
ART Fertility Clinics LLC
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates, 60202
Actively Recruiting
2
ART Fertility Clinics Dubai
Dubai, United Arab Emirates
Actively Recruiting
Research Team
B
Barbara Lawrenz, PhD
CONTACT
J
Jonalyn Edades, RN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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