Actively Recruiting
Optimisation of Decision Making for Defibrillator Implantation in Hypertrophic Cardiomyopathy
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2023-03-16
2000
Participants Needed
1
Research Sites
335 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main objective of the study is to improve implantable cardioverter defibrillator (ICD) implantation decision-making processing relevance by developing a new prediction model of sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM), including newly identified potential biomarkers by magnetic resonance imaging (MRI) and genetics, through a prospective nationwide study, multivariate analysis and modelling of an absolute risk. The secondary objective is to perform a medico-economic analysis of ICD implantation in order to define an optimal rule for ICD implantation in patients with HCM, taking into account the benefits of ICD, adverse effects of ICD and associated costs (cost of quality adjusted life years saved).
CONDITIONS
Official Title
Optimisation of Decision Making for Defibrillator Implantation in Hypertrophic Cardiomyopathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with hypertrophic cardiomyopathy (HCM) based on standard criteria (left ventricle wall thickness 15 mm in adults or 13 mm in adult relatives) without abnormal loading conditions
- Aged 16 years or older
- Patient without a defibrillator or with a defibrillator implanted for primary prevention
- Affiliated to a social security insurance
You will not qualify if you...
- Specific causes such as amyloidosis
- Patients with defibrillators implanted for secondary prevention after aborted sudden cardiac death or sustained ventricular arrhythmia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Centre de référence pour les cardiomyopathies et les troubles du rythme héréditaires ou rares - UF de Génétique, Hôpital Ambroise Paré,
Boulogne-Billancourt, Hauts-de-Seine, France, 92100
Actively Recruiting
Research Team
P
Philippe CHARRON, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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