Early Optimized Care During Post-Operative Radiochemotherapy for Head and Neck Squamous Cell Carcinoma

What this Trial Is About

Researchers are evaluating an optimized early management approach for patients with squamous cell carcinoma of the head and neck who are undergoing post-operative radiochemotherapy. This treatment is challenging due to recent surgery, hospitalization, weight loss, and difficulty in feeding during radiotherapy. The study aims to improve treatment completion rates and patient outcomes by providing a harmonized nutritional and supportive care strategy. Participants in the experimental group will receive early consultations with a nutritionist, pain specialist, and social worker at inclusion. During radiotherapy preparation, weekly visits with a pain nurse and dietician are planned. Throughout radiotherapy, patients will have daily weight checks, nutritional assessments, and weekly consultations with a pain nurse and dietician, then twice monthly follow-ups for three months post-treatment. The control group will receive standard care and monitoring. During the study, researchers will monitor weight loss from inclusion to three months post-treatment as the primary outcome. Secondary outcomes include overall and progression-free survival at 18 months, treatment completion rates, use of strong pain medications, average weight loss at 18 months, and a cost-utility analysis of the management approach. Participants will be followed for 18 months to assess these measures and support will be provided throughout the study period.

Optimised Early Management of Squamous Cell Carcinoma of the Head and Neck Cancer