Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05929144

Optimization of MRI Sequences Used in the Study of Neurodegenerative Diseases

Led by University Hospital, Caen · Updated on 2023-07-03

40

Participants Needed

1

Research Sites

269 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The Inserm NeuroPresage team has been using MRI for more than 20 years in the study of normal ageing and memory pathologies to further the understanding and the characterization of early diagnosis and the cerebral substrates of cognitive deficits in patients, particularly in the context of neurodegenerative diseases. Two years ago, a new 3T MRI camera was installed at the Cyceron centre. It is more efficient and should make it possible to obtain better quality images and/or to reduce the time required to acquire these images. In this context, it seems important to test the different sequences that we classically use in our studies, or that we plan to implement in our next studies (learning and text retrieval fMRI task), in order to optimize them, with a view to integrating them in our future studies.

CONDITIONS

Official Title

Optimization of MRI Sequences Used in the Study of Neurodegenerative Diseases

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy volunteers of legal age
  • Affiliation with a social security scheme or beneficiary of such a scheme
  • Signing of the protocol informed consent
  • For women of childbearing age or capacity, a urine pregnancy test before inclusion
Not Eligible

You will not qualify if you...

  • Protected persons as defined by French Public Health Code articles L. 1121-5 to L.1121-8, including protected adults and pregnant or nursing women
  • Contraindications to MRI examination without contrast agent injection
  • Presence of chronic neurological or psychiatric conditions, including substance use disorder
  • History of brain disease such as vascular, degenerative, malformative, tumor, or head trauma with loss of consciousness lasting more than one hour
  • Current or recent use of medications that may interfere with imaging, including psychotropic drugs, antihistamines with anticholinergic effects, antiparkinsonian drugs, benzodiazepines including muscle relaxants, long-term steroidal anti-inflammatory drugs, antiepileptic drugs, or central painkillers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

GIP Cyceron

Caen, France, 14000

Actively Recruiting

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Research Team

G

Géraldine Poisnel, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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Optimization of MRI Sequences Used in the Study of Neurodegenerative Diseases | DecenTrialz