Actively Recruiting
Optimization of a Non-invasive Electrophysiological Method for Studying the Functionality of Auditory Nerve Fibers
Led by University Hospital, Clermont-Ferrand · Updated on 2023-08-09
430
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Clermont-Ferrand
Lead Sponsor
L
Laboratory of Neurosensory Biophysics - UMR INSERM 1107.
Collaborating Sponsor
AI-Summary
What this Trial Is About
Acoustic overexposure can induced temporary or hearing loss. Usually hearing loss is associated with cochlear cell damages. Recently, a new pathological entity was described and called "hidden hearing loss". In animal model, the histopathology revealed a selective reduction in the number of auditory fibers, resulting in a decrease in the amplitude of wave I of the auditory brainstem response. Electrocochleography (Ecog) is a method for recording the electrical potentials of the cochlea (e.g. wave I). In clinical routine, Ecog is performed invasively with sedation or local anesthesia. Actually, a non invasive approach could be perform but it seems necessary to optimize this method and to define reference values in healthy volunteers.
CONDITIONS
Official Title
Optimization of a Non-invasive Electrophysiological Method for Studying the Functionality of Auditory Nerve Fibers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between 18 and 55 years old
- Affiliated to a social security system
- Understand spoken and written French
- Normal hearing with normal tympanogram and audiogram
You will not qualify if you...
- Complaint of hearing problems
- Exposure to loud noise professionally or through activities
- Refusal to participate in the study
- Ear infections or ear, nose, and throat medical history
- Cardiovascular, metabolic, neurological, or psychiatric diseases
- Being a protected person
- Healthy volunteers who have received compensation of 4500ac or more in clinical studies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Chu Clermont Ferrand
Clermont-Ferrand, France, 63003
Actively Recruiting
Research Team
L
Lise Laclautre
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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