Actively Recruiting

Phase 2
Age: 18Years +
FEMALE
NCT05872724

Optimization of Postoperative Adjuvant Therapy for Cervical Cancer Based on MRD(Minimal Residual Disease)

Led by Suzhou Municipal Hospital · Updated on 2023-05-24

32

Participants Needed

1

Research Sites

310 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a prospective cohort clinical trial that aims to investigate the safety and efficacy of a combined chemoradiotherapy and immunotherapy treatment for early postoperative cervical cancer. Specifically, this study seeks to evaluate the ability of MRD-based screening to detect and monitor changes in MRD status at different stages of treatment, its potential for use in monitoring patient recurrence rates and in prognosis evaluation. In addition, this study will investigate the safety and effectiveness of chemoradiotherapy combined with immunotherapy as a postoperative adjuvant therapy for patients identified to be at risk of early cervical cancer based on MRD screening.

CONDITIONS

Official Title

Optimization of Postoperative Adjuvant Therapy for Cervical Cancer Based on MRD(Minimal Residual Disease)

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with histopathological and clinical (FIGO 2018) stage IB2 to IIA2 cervical cancer.
  • Age 18 years or older.
  • ECOG performance status score of 0 to 2.
  • Able to understand the study and voluntarily sign informed consent.
  • Good compliance and able to provide specimens and clinical information as required.
Not Eligible

You will not qualify if you...

  • Having other malignant tumors.
  • Not receiving the specified treatment or changing treatment before disease progression.
  • Unable to follow the study's clinical follow-up schedule.
  • Unable to accept or provide CT scans or other required therapeutic evaluations.
  • Having an autoimmune disease.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Affiliated Suzhou Hospital of Nanjing Medical University

Suzhou, Jiangsu, China, 215001

Actively Recruiting

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Research Team

J

jing xue

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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