What this Trial Is About

Researchers are investigating new surgical methods to improve treatment outcomes for patients with medium to large postoperative ventral hernias located in the middle and middle-lateral areas of the abdominal wall. The study aims to better understand the anatomy of blood vessels and nerves in various layers of the abdominal wall to reduce complications and enhance recovery. This research addresses the high frequency of postoperative complications such as seromas and wound issues seen with current treatments using mesh implants. The study compares an experimental surgical technique designed to minimize damage to blood vessels and nerves during hernia repair with standard treatment methods. Researchers will develop and test new ways to prepare the implant site and combine different tissue layers for optimal hernia repair. This includes preserving important neurovascular bundles and reducing risks of bleeding and nerve pain. The study involves both anatomical research on cadavers and clinical testing on patients over the next 1.5 to 2 years. Participants will undergo detailed imaging like CT scans before surgery and ultrasound monitoring afterward to assess fluid buildup and other complications. The study will measure outcomes such as rates of seroma and hematoma within five days post-surgery, as well as hernia recurrence over one year. Researchers will also evaluate pain levels, treatment duration, and both immediate and long-term complications up to 1.5 years. Data analysis will include advanced statistical methods to determine the effectiveness of the new surgical techniques compared to standard care.

Optimization of Surgical Treatment of Patients With Incisional Ventral Hernias