Actively Recruiting

Age: 3Years - 60Years
All Genders
ID07009652

Proposal for the Organisation of the Procedure for Extracorporeal Cardiopulmonary Resuscitation of Patients With Sudden Cardiac Arrest in the Pre-hospital Environment of the Moravian-Silesian Region

Led by University Hospital Ostrava · Updated on 2025-06-06

100

Participants Needed

2

Research Sites

104 weeks

Total Duration

On this page

Sponsors

U

University Hospital Ostrava

Lead Sponsor

E

Emergency Medical Services, Moravian-Silesian Region

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying how to improve the care and outcomes for patients who experience sudden cardiac arrest outside of a hospital in the Moravian-Silesian Region. The study focuses on evaluating the use of a mobile extracorporeal membrane oxygenation (ECMO) team and optimizing patient transport to reduce the time from collapse to the start of ECMO treatment. This aims to enhance neurological recovery after resuscitation. The main intervention involves patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR), which is a procedure that oxygenates the patient's blood using a machine during resuscitation. The study will analyze regional data to identify factors that help shorten the time until ECMO begins and support the development of better protocols for pre-hospital ECPR. The mobile ECMO team will be dispatched to the scene to initiate this treatment. Participants will be monitored for neurological outcomes 30 days after treatment using a CPC score. Researchers will also measure key time intervals such as the time from collapse to ECMO initiation, transport time to the ECMO center, and arrival time of the mobile ECMO team, all within two hours. The study is observational and will take place from May 2025 through May 2028, tracking patient data and outcomes related to sudden cardiac arrest and rescue with ECPR.

CONDITIONS

Brief Title

Optimization of Transport and Use of a Mobile ECMO Team in Patients With Sudden Cardiac Arrest in the Moravian-Silesian Region

Who Can Participate

Age: 3Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Out-of-hospital cardiac arrest
  • Indication for extracorporeal cardiopulmonary resuscitation (ECPR)
  • Age between 3 and 60 years
Not Eligible

You will not qualify if you...

  • Death at the scene of the accident
  • Withdrawal of informed consent to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Extracorporeal cardiopulmonary resuscitation (ECPR)

Duration - Up to 2 hours

Participants undergo extracorporeal cardiopulmonary resuscitation (ECPR) as part of emergency care following sudden cardiac arrest.

Single emergency intervention

Monitoring

Duration - 30 days

Participants are observed to assess neurological outcomes and other clinical measures after ECPR.

Follow-up visits as needed for up to 30 days

Trial Site Locations

Total: 2 locations

1

Emergency Medial Services, Moravian-Silesian Region

Ostrava, Moravian-Silesian Region, Czechia, 70030

Actively Recruiting

2

University Hospital Ostrava

Ostrava, Moravian-Silesian Region, Czechia, 70852

Actively Recruiting

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Research Team

J

Jiří Hynčica

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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