Actively Recruiting
Optimized Ablation of the Posterior Wall in Persistent Atrial Fibrillation
Led by Shanghai Chest Hospital · Updated on 2025-08-14
384
Participants Needed
1
Research Sites
76 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The design of this study is an intervention, randomized, controlled study and contains three randomized groups：（1）PVI group；（2）PVI+PWI group;（3）PVI+PWI+EGM group.
CONDITIONS
Official Title
Optimized Ablation of the Posterior Wall in Persistent Atrial Fibrillation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- First-time ablation for persistent atrial fibrillation
- Persistent AF lasting 7 days to less than 3 years, including episodes needing cardioversion after 7 days
- Symptomatic AF not controlled by at least one antiarrhythmic drug
- At least one documented episode of persistent AF in the last 2 years confirmed by ECG, Holter monitoring, loop recorder, telemetry, transtelephonic monitoring, or implantable device
- Ability and willingness to provide written informed consent
- Willingness to comply with all study follow-up requirements
You will not qualify if you...
- Paroxysmal AF with episodes lasting less than 7 days or needing cardioversion within 7 days
- Long-standing persistent AF lasting more than 3 years continuously
- No prior attempt at cardioversion or maintaining normal heart rhythm
- Contraindications to systemic anticoagulation
- Pregnancy
- Advanced kidney or liver failure
- Severe valvular heart disease or cyanotic congenital heart disease
- Hypertrophic cardiomyopathy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Shanghai Chest Hospital
Shanghai, China
Actively Recruiting
Research Team
M
Mu Qin
CONTACT
X
Xumin Hou
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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