Actively Recruiting
Optimizing a Bio-behavioral Intervention for Sustained Viral Suppression
Led by University of Texas, El Paso · Updated on 2024-09-03
220
Participants Needed
1
Research Sites
168 weeks
Total Duration
On this page
Sponsors
U
University of Texas, El Paso
Lead Sponsor
U
University of California, San Francisco
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study will test two behavioral intervention components to identify the combination of the two components that best supports people who inject drugs to achieve and sustain HIV viral load suppression. The study design is a 2-to-the-2 factorial experiment. The 2 represents the level of each component: 0 (receive) or 1 (don't receive). The 2 represents the number of components being tested. The four components are: 1) receiving (or not receiving) peer support services for medication-assisted treatment (MAT) uptake and persistence and 2) behavioral activation therapy for depression (BAT). Therefore, in order to test which combination of components produce the best outcome, this factorial design randomizes people to 1 of 4 conditions. Each condition represents a possible combination of the 2 components above. All participants will receive patient navigation for care engagement.
CONDITIONS
Official Title
Optimizing a Bio-behavioral Intervention for Sustained Viral Suppression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be at least 18 years old
- Able to provide informed consent
- Eligible to receive free HIV care services in Mexico
- HIV positive
- Have injected drugs in the last 30 days
- Not currently on methadone replacement therapy
- Willing to discuss medication-assisted treatment (MAT) uptake with a peer
- Sign a medical release form to allow medical data abstraction
- Agree to provide and describe locator information
- Agree to return for follow-up visits
- Able to communicate in Spanish
- Screen positive for depression on the PHQ-2
- Have no plans to move outside the study area in the next 12 months
- Meet one of the following regarding ART or viral load status:
- Not currently in possession of ART or not taking ART but prescribed ART
- Sub-optimal ART adherence with at least one 4-day treatment interruption in the past 90 days
- Sub-optimal retention in HIV care with two or more missed clinic appointments in the last 9 months
- No viral load test done in the past six months
- Self-reports a detectable viral load within the past 6 months
You will not qualify if you...
- Have not injected drugs in the last 30 days or do not have a verifiable opioid use disorder
- Not HIV positive
- Currently receiving methadone treatment
- Unwilling to discuss methadone uptake with a peer
- Do not screen positive for depression
- Unable to provide informed consent
- Do not speak Spanish
- Have plans to move out of the city
- Not eligible to receive free HIV care services in Mexico
- Appear to have psychological disturbance or severe cognitive impairment that could limit understanding of study procedures as determined by study staff
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Programa Compañeros
Ciudad Juárez, Chihuahua, Mexico, 32330
Actively Recruiting
Research Team
J
Julia Lechuga, PhD
CONTACT
J
John A Sauceda, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
4
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here