Actively Recruiting
Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Novel Diagnostics
Led by Jeffrey · Updated on 2024-12-10
75
Participants Needed
1
Research Sites
89 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Children are commonly hospitalized because of community-acquired pneumonia. Despite the fact that many of these children have viral disease, a majority is treated with antibiotics. These antibiotics will not accelerate recovery in those with viral pneumonia and can cause harm. We are interested in exploring whether the MeMed BV - a composite biomarker assay - could be used to improve antibiotic prescribing in these children by identifying those who likely have viral disease. This proposal describes a feasibility randomized trial of this diagnostic intervention.
CONDITIONS
Official Title
Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Novel Diagnostics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children hospitalized with community-acquired pneumonia and a history of fever
- Abnormal chest imaging such as radiograph or ultrasound
- At least one of the following: documented fast breathing, cough, increased work of breathing, or lung exam findings consistent with pneumonia
You will not qualify if you...
- Received more than 48 hours of intravenous antibiotics before enrollment
- Lobar consolidation occupying most of a lung lobe on imaging
- Pleural effusion occupying more than one-quarter of a lung field
- Positive blood culture for a bacterial pathogen (excluding contaminants)
- Chronic lung disease
- Congenital heart disease requiring treatment or exercise restrictions
- Malignancy
- Immunodeficiency (primary, acquired, or treatment-related)
- Another pneumonia episode diagnosed within the past 2 weeks
- Lung abscess diagnosed within the past 6 months
- Participation in the study more than once
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
McMaster Children's Hospital
Hamilton, Ontario, Canada, L8S 4K1
Actively Recruiting
Research Team
J
Jeffrey Pernica, MD
CONTACT
S
Shamini Selvakumar, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here