Actively Recruiting
Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
Led by University of Michigan · Updated on 2026-02-13
900
Participants Needed
3
Research Sites
225 weeks
Total Duration
On this page
Sponsors
U
University of Michigan
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The proposed study focuses on testing a novel adapted evidence-based multilevel intervention, Deprescribing Thyroid Hormone In Older Adults (D-THIO), to support thyroid hormone deprescribing (dose de-escalation and/or discontinuation) in older adults with thyroid hormone overtreatment and/or misuse and reduce patient harm. Findings from this study will lay the groundwork for broad implementation of D-THIO and serve as a model for deprescribing inappropriate medications for other endocrine conditions and conditions with biochemical monitoring.
CONDITIONS
Official Title
Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 65 years and older
- Receiving thyroid hormone therapy with a serum Thyroid-stimulating hormone (TSH) level less than 0.5 mIU/L or on thyroid hormone therapy for an inappropriate reason
- English speaking
- No cognitive impairment
- Providers must be primary care physicians, endocrinologists, geriatricians, or advanced practice providers who prescribe thyroid hormone and practice at University of Michigan, Henry Ford Health System, or University of California San Francisco
You will not qualify if you...
- Diagnosis of thyroid cancer
- Secondary hypothyroidism
- History of total thyroidectomy
- Hospitalization in the past 3 months
- Providers who do not prescribe thyroid hormone
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
University of California San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
2
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
3
Henry Ford Health System
Detroit, Michigan, United States, 48202
Actively Recruiting
Research Team
B
Brittany Gay
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here