Actively Recruiting
Optimizing the Care Pathway of Febrile Children Via Capillary C-reactive Protein Assay in Primary Care
Led by Centre Hospitalier Universitaire de Nīmes · Updated on 2025-11-19
420
Participants Needed
16
Research Sites
23 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Fever is the leading reason for outpatient consultations among children aged 2 to 9 years. The main concern in fever is severe bacterial infection, particularly for younger children. History and clinical examination do not always differentiate viral infections from bacterial infection. In 20% of febrile children, no infectious focus is found after examination and additional tests are necessary. The first one is measuring C-reactive protein (CRP). The results are obtained in several hours on an outpatient basis, causing long delays before starting treatment and often requiring telephone calls or further consultations. Emergency room use is constantly increasing, generating growing tensions within healthcare facilities, yet a large number of visits are avoidable. Among children visiting the pediatric emergency room, parents reported being referred by their primary care physician in approximately 20% of cases for children aged 1 to 5 years and in 30% of cases for children under one year old. The use of capillary medical device to measure CRP in primary care could reduce this referral rate and help relieve overcrowding in emergency rooms, as well as unscheduled consultation centers and medical analysis laboratories. This would result in a streamlined care pathway, saving time for both physicians and patients, as well as reducing the cost of care for the healthcare system.
CONDITIONS
Official Title
Optimizing the Care Pathway of Febrile Children Via Capillary C-reactive Protein Assay in Primary Care
Who Can Participate
Eligibility Criteria
You may qualify if you...
- The patient must be a member or beneficiary of a health insurance plan
- Children consulting primary health institutes with fever (temperature 64 386C) requiring CRP testing
- Fever > 12 hours in infants aged 3 to 6 months
- Fever 65 days in children over 6 months of age
- Fever >12 hours regardless of age with doctor concern about general condition, fever tolerance, or possible bacterial infection
- No severity criteria requiring immediate hospitalization
- No bacterial infection diagnosed exclusively by clinical signs or other means
- Parents and child informed about the study and at least one parent consented
- Enrollment according to child's capacity of discernment for children aged 12 and over
- Child affiliated with or benefiting from a health insurance scheme
You will not qualify if you...
- Participation in a category 1 interventional study or a study with drug or medical device
- Premature infants under one year of age
- Immunosuppression
- Sunstroke
- Chronic infection
- Malignant disease
- Autoimmune disease
- Sickle cell disease
- Child with a central catheter
AI-Screening
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Trial Site Locations
Total: 16 locations
1
MSP OLEA
Bezouce, France
Actively Recruiting
2
MSP Espace Santé Servian
Béziers, France
Actively Recruiting
3
MSPU Avicenne
Cabestany, France
Actively Recruiting
4
MSP de Calvisson
Calvisson, France
Actively Recruiting
5
MSP de Clarensac
Caveirac, France
Actively Recruiting
6
MMG de Montpellier
Montpellier, France
Actively Recruiting
7
MSP Montpellier-Cévennes
Montpellier, France
Actively Recruiting
8
MMG de Narbonne
Narbonne, France
Actively Recruiting
9
CHU de Nîmes
Nîmes, France
Actively Recruiting
10
MMG de Nîmes
Nîmes, France
Actively Recruiting
11
MSP de Pont Saint Esprit
Pont-Saint-Esprit, France
Actively Recruiting
12
MSPU Pauline Lautaud
Prades-le-Lez, France
Actively Recruiting
13
MSP Le Prisme
Remoulins, France
Actively Recruiting
14
MSP Saint-Laurent d'Aigouze
Saint-Laurent-d'Aigouze, France
Actively Recruiting
15
MSP Sud Minervois
Saint-Marcel-sur-Aude, France
Actively Recruiting
16
Mspu La Source
Vergèze, France
Actively Recruiting
Research Team
C
Chloé SIKIRDJI
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
2
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