Actively Recruiting

Phase Not Applicable
Age: 3Months - 15Years
All Genders
NCT06910631

Optimizing the Care Pathway of Febrile Children Via Capillary C-reactive Protein Assay in Primary Care

Led by Centre Hospitalier Universitaire de Nīmes · Updated on 2025-11-19

420

Participants Needed

16

Research Sites

23 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Fever is the leading reason for outpatient consultations among children aged 2 to 9 years. The main concern in fever is severe bacterial infection, particularly for younger children. History and clinical examination do not always differentiate viral infections from bacterial infection. In 20% of febrile children, no infectious focus is found after examination and additional tests are necessary. The first one is measuring C-reactive protein (CRP). The results are obtained in several hours on an outpatient basis, causing long delays before starting treatment and often requiring telephone calls or further consultations. Emergency room use is constantly increasing, generating growing tensions within healthcare facilities, yet a large number of visits are avoidable. Among children visiting the pediatric emergency room, parents reported being referred by their primary care physician in approximately 20% of cases for children aged 1 to 5 years and in 30% of cases for children under one year old. The use of capillary medical device to measure CRP in primary care could reduce this referral rate and help relieve overcrowding in emergency rooms, as well as unscheduled consultation centers and medical analysis laboratories. This would result in a streamlined care pathway, saving time for both physicians and patients, as well as reducing the cost of care for the healthcare system.

CONDITIONS

Official Title

Optimizing the Care Pathway of Febrile Children Via Capillary C-reactive Protein Assay in Primary Care

Who Can Participate

Age: 3Months - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • The patient must be a member or beneficiary of a health insurance plan
  • Children consulting primary health institutes with fever (temperature 64 386C) requiring CRP testing
  • Fever > 12 hours in infants aged 3 to 6 months
  • Fever 65 days in children over 6 months of age
  • Fever >12 hours regardless of age with doctor concern about general condition, fever tolerance, or possible bacterial infection
  • No severity criteria requiring immediate hospitalization
  • No bacterial infection diagnosed exclusively by clinical signs or other means
  • Parents and child informed about the study and at least one parent consented
  • Enrollment according to child's capacity of discernment for children aged 12 and over
  • Child affiliated with or benefiting from a health insurance scheme
Not Eligible

You will not qualify if you...

  • Participation in a category 1 interventional study or a study with drug or medical device
  • Premature infants under one year of age
  • Immunosuppression
  • Sunstroke
  • Chronic infection
  • Malignant disease
  • Autoimmune disease
  • Sickle cell disease
  • Child with a central catheter

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 16 locations

1

MSP OLEA

Bezouce, France

Actively Recruiting

2

MSP Espace Santé Servian

Béziers, France

Actively Recruiting

3

MSPU Avicenne

Cabestany, France

Actively Recruiting

4

MSP de Calvisson

Calvisson, France

Actively Recruiting

5

MSP de Clarensac

Caveirac, France

Actively Recruiting

6

MMG de Montpellier

Montpellier, France

Actively Recruiting

7

MSP Montpellier-Cévennes

Montpellier, France

Actively Recruiting

8

MMG de Narbonne

Narbonne, France

Actively Recruiting

9

CHU de Nîmes

Nîmes, France

Actively Recruiting

10

MMG de Nîmes

Nîmes, France

Actively Recruiting

11

MSP de Pont Saint Esprit

Pont-Saint-Esprit, France

Actively Recruiting

12

MSPU Pauline Lautaud

Prades-le-Lez, France

Actively Recruiting

13

MSP Le Prisme

Remoulins, France

Actively Recruiting

14

MSP Saint-Laurent d'Aigouze

Saint-Laurent-d'Aigouze, France

Actively Recruiting

15

MSP Sud Minervois

Saint-Marcel-sur-Aude, France

Actively Recruiting

16

Mspu La Source

Vergèze, France

Actively Recruiting

Loading map...

Research Team

C

Chloé SIKIRDJI

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Optimizing the Care Pathway of Febrile Children Via Capillary C-reactive Protein Assay in Primary Care | DecenTrialz