Actively Recruiting

Phase Not Applicable
Age: 40Years - 89Years
All Genders
NCT03995238

Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation

Led by VA Office of Research and Development · Updated on 2026-04-13

54

Participants Needed

2

Research Sites

368 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The population of older Veterans with non-traumatic lower limb amputation is growing. Following lower limb amputation, asymmetrical movements persist during walking and likely contribute to disabling sequelae including secondary pain conditions, poor gait efficiency, impaired physical function, and compromised skin integrity of the residual limb. This study seeks to address chronic gait asymmetry by evaluating the efficacy of two error-manipulation gait training programs to improve gait symmetry for Veterans with non-traumatic lower limb amputation. Additional this study will evaluate the potential of error-manipulation training programs to improve secondary measures of disability and residual limb skin health. Ultimately, this study aims to improve conventional prosthetic rehabilitation for Veterans with non-traumatic amputation through gait training programs based in motor learning principles, resulting in improved gait symmetry and lower incidence of long-term disability after non-traumatic lower limb amputation.

CONDITIONS

Official Title

Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation

Who Can Participate

Age: 40Years - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Unilateral, non-traumatic, transtibial amputation
  • Diabetes mellitus and/or peripheral artery disease
  • Able to ambulate in the community without assistive device
  • Step length asymmetry during walking (>1.0 asymmetry index)
  • At least 6 months since amputation
Not Eligible

You will not qualify if you...

  • Unstable heart condition, including unstable angina, uncontrolled cardiac dysrhythmia, acute myocarditis, hypertension, and acute pericarditis
  • Acute systemic infection
  • Active cancer treatment
  • Amputation caused by trauma or cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Rocky Mountain Regional VA Medical Center, Aurora, CO

Aurora, Colorado, United States, 80045-7211

Actively Recruiting

2

Hunter Holmes McGuire VA Medical Center, Richmond, VA

Richmond, Virginia, United States, 23249

Actively Recruiting

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Research Team

C

Cory L Christiansen, PhD

CONTACT

R

Ryan Stephenson, DO

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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