Actively Recruiting
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen
Led by University of California, San Francisco · Updated on 2026-04-13
10
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy adults, ages 18-75. The main questions it aims to answer are: * Does breath-holding at end-expiration improve image quality in abdominal MRI scans? * Does adding oxygen while breath-holding further reduce motion artifacts in abdominal MRI scans? Researchers will compare breath-holding with and without oxygen to see if using oxygen improves image quality during MRI scans. Participants will: * Be pre-screened for MRI safety and trained on breath-hold procedures * Have one non-contrast abdominal MRI scan at the University of California San Francisco (UCSF) China Basin Imaging Center * Use two different breath-holding techniques during the scan, with and without oxygen * Complete one study visit lasting about 45 minutes to 1 hour
CONDITIONS
Official Title
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between 18 and 75 years of age
- Able to hear and understand instructions without assistive devices
- Willing to provide written informed consent
- Have the mental capacity to understand instructions and comply with the study
- Able to remain still for about 30 to 45 minutes during the imaging procedure
You will not qualify if you...
- Weigh more than 499 pounds
- Have metallic, conductive, or electrically/magnetically active implants that are not labeled MR Safe or MR Conditional, except for dental devices/fillings, surgical clips, or staples deemed safe by a physician
- Have implants labeled MR Unsafe
- Have MR Conditional implants that cannot meet safe conditions during MRI
- Have any contraindication to MRI according to site screening
- Have respiratory or cardiovascular conditions that could make breath-holding unsafe
- Are female and pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California, San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
Research Team
J
John P Roberts, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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