Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06651736

Optimizing Low Vision Rehabilitation in Emotionally Distressed Patients With Inherited Retinal Diseases

Led by University of Michigan · Updated on 2026-03-23

180

Participants Needed

1

Research Sites

201 weeks

Total Duration

On this page

Sponsors

U

University of Michigan

Lead Sponsor

N

National Eye Institute (NEI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to understand if combining Low Vision Rehabilitation (LVR) with Emotional Regulation Therapy (ERT) can help people with inherited retinal diseases (IRDs) that experience emotional distress related to participants' vision loss. The study team hypothesize that treatment with LVR will produce measurable functional gains and that these effects will be enhanced by ERT-linked improvement among the subgroup of IRD patients with elevated vision-related anxiety.

CONDITIONS

Official Title

Optimizing Low Vision Rehabilitation in Emotionally Distressed Patients With Inherited Retinal Diseases

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with vision impairment caused by inherited retinal disease (IRD)
  • Had a clinical exam with an IRD specialist within the last three months
  • Had a Goldmann visual field test with III-4e isopter within the past year
  • Have a disability greater than zero theta in any domain of the Michigan Retinal Dystrophy Questionnaire (MRDQ)
  • IRD specialist indicates ocular condition will not worsen over the next year
  • Able to participate in 10 weeks of Emotional Regulation Therapy sessions while located in Michigan
Not Eligible

You will not qualify if you...

  • Have other eye conditions including cystoid macular edema (CME) related to IRD
  • Functional low vision needs have been adequately addressed by a low vision specialist
  • Currently receiving mental health therapy
  • Elevated suicidal intention or suicide risk based on screening questionnaires
  • Using mental health medication but not on a stable dose for at least 1 month
  • Unable to complete study tasks

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Michigan

Ann Arbor, Michigan, United States, 48105

Actively Recruiting

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Research Team

J

Jessica Stout

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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