Actively Recruiting
Optimizing an Online Behavioral Weight Loss Program with Tailored Components for Sexual Minority Women: MOST Optimization Phase
Led by The Miriam Hospital · Updated on 2024-12-27
88
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
Sponsors
T
The Miriam Hospital
Lead Sponsor
N
National Institute on Minority Health and Health Disparities (NIMHD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Obesity disproportionately affects sexual minority women, and behavioral weight loss programs are the standard treatment for mild to moderate obesity. Researchers developed an online behavioral weight loss program called Rx Weight Loss that is effective, low-cost, and scalable. To improve relevance and effectiveness, they created three new components tailored to address barriers common in sexual minority women: minority stress, low social support, and negative body image. This phase of the study aims to optimize these components using a factorial experiment with 88 women over six months. Participants will receive 12 weeks of the Rx Weight Loss program, which includes weekly online video lessons, self-monitoring of weight, calorie intake, and activity, plus personalized automated feedback. They will be randomized to receive 0 to 3 of the novel tailored components: a minority stress intervention teaching coping strategies, a social support intervention providing an online forum, and a negative body image intervention offering cognitive behavioral therapy skills. Each component consists of weekly 8-10 minute lessons delivered alongside the main program. During the study, participants will regularly submit data and engage with the online lessons and support platform. Researchers will measure changes in weight and the proportion achieving at least 5% weight loss at 6 months. They will also explore how the tailored components affect weight loss through mechanisms like stress coping and social support. The study includes safety monitoring and adherence encouragement through reminders. The overall goal is to finalize an optimized online behavioral obesity treatment tailored for sexual minority women.
CONDITIONS
Official Title
Optimizing an Online Behavioral Weight Loss Intervention and Novel Culturally Tailored Components for Sexual Minority Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Assigned female at birth and currently identify as female
- Self-identify as a sexual minority (e.g., lesbian, bisexual)
- Body mass index (BMI) between 25 and 50 kg/m2
- Aged 18 to 70 years old
- Interested in losing weight
- Have regular internet and email access
- No significant weight loss (>5%) in the past 6 months
- Fluent in English
- Able to participate in moderate physical activity
- Not currently enrolled in a weight loss program
- Not currently taking weight-loss medication
- Not currently pregnant or trying to get pregnant
You will not qualify if you...
- Previously participated in a prior phase of this study
- Report a serious mental or physical health condition that increases treatment risks, such as active psychosis, suicidality, mania, alcohol or substance use disorder
- Have a serious, active, unstable, or degenerative medical condition (e.g., congestive heart failure)
AI-Screening
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Trial Site Locations
Total: 1 location
1
Weight Control and Diabetes Research Center
Providence, Rhode Island, United States, 02903
Actively Recruiting
Research Team
E
Emily Panza, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
TREATMENT
Number of Arms
8
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