Long-term analgesic use after low-risk surgery: a retrospective cohort study.
Asim Alam, Tara Gomes, Hong Zheng...
https://pubmed.ncbi.nlm.nih.gov/22412106Actively Recruiting
Led by Benaroya Research Institute · Updated on 2019-09-27
50
Participants Needed
1
Research Sites
8 weeks
Total Duration
B
Benaroya Research Institute
Lead Sponsor
V
Virginia Mason Hospital/Medical Center
Collaborating Sponsor
Researchers are evaluating a new approach to managing pain after transurethral resection of the prostate (TURP) that aims to reduce opioid use. The study compares a multi-modal pain control protocol, which combines two or more pain relief agents acting by different mechanisms, to the current standard care that primarily uses opioids. The goal is to provide similar pain relief while minimizing opioid use, addressing concerns related to the opioid epidemic in surgical patients. Participants are randomly assigned to one of two groups. The standard care group receives medications including topical lidocaine gel, acetaminophen, oxycodone, and other supportive drugs both during hospitalization and after discharge. The multi-modal group receives a regimen that adds ibuprofen and patient education about pain and opioid use, aiming to reduce opioid consumption. Both groups get similar supportive medications for urinary symptoms and constipation. The study period includes inpatient treatment and discharge medication prescriptions. During the study, participants' opioid use and pain levels are monitored from post-anesthesia care through 72 hours after surgery. Researchers also track the presence of urinary catheters at discharge, side effects from narcotics within 48 hours after discharge, and any post-operative complications. Participants are evaluated through medication usage records and pain scores to assess the effectiveness of the pain management protocols, ensuring careful monitoring of safety and outcomes throughout the study.
CONDITIONS
Optimizing Pain Control in Transurethral Resection of the Prostate
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Hospital stay (0 to 48 hours)
Participants undergo transurethral resection of the prostate (TURP) and receive assigned pain control management while hospitalized, either standard care or a multi-modal pain management protocol including medication and education.
1 hospital stay with medication administration
Duration - Up to 72 hours after surgery
Participants are monitored for pain control, opioid consumption, presence of urinary catheter, narcotic side effects, and any post-operative complications after discharge.
Follow-up assessments within 72 hours post-surgery
Total: 1 location
1
Virginia Mason Medical Center
Seattle, Washington, United States, 98101
Actively Recruiting
R
Ryan Donahue, MD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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