Actively Recruiting
Optimizing Pain Self-Management in Total Knee Arthroplasty Using Savoring Meditation Compared to Pain Education
Led by University of Virginia · Updated on 2023-12-06
150
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating a positive affect enhancing intervention called Savoring Meditation to reduce pain and improve reward system function in patients with knee osteoarthritis undergoing total knee arthroplasty (TKA). The study aims to compare this approach with Pain Self-Management and Education (PSME) to address persistent pain and psychological distress after surgery. The trial focuses on psychosocial factors influencing recovery and tests a novel meditation practice combined with pain neuroscience education to improve outcomes. Participants will be randomly assigned to one of two groups: Savoring Meditation or Pain Self-Management and Education. Each group will receive four remote, one-on-one sessions lasting 20-30 minutes. The Savoring Meditation group will learn to generate positive emotions through meditation and understand the brain's reward system related to pain, while the PSME group will learn about biological, psychological, and social contributors to chronic pain. Participants are encouraged to practice meditation daily after surgery and to use it as a tool for pain management. During the study, participants will complete questionnaires and weeklong ecological momentary assessments at baseline, after surgery, and at a 3-month follow-up. Laboratory sessions at baseline and 6 weeks post-surgery will measure brain activity and pain modulation. Researchers will assess clinical pain levels, opioid use, joint function, and positive affect. The study will monitor participants for up to 3 months to evaluate the impact of the interventions on pain and recovery after TKA.
CONDITIONS
Brief Title
Optimizing Pain Self-Management in Total Knee Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 85 years
- Physician-confirmed plan for unilateral total knee arthroplasty
- Physician-confirmed diagnosis of knee osteoarthritis
- Willingness and ability to follow scheduled sessions and study procedures
You will not qualify if you...
- Pregnant women, children, prisoners, cognitively impaired, or non-English-speaking individuals
- Current unstable or severe medical condition
- Severe psychiatric disorders such as schizophrenia or psychosis
- Severe alcohol or substance use disorder
- Weekly or more frequent opioid use in past 30 days (except tramadol or codeine)
- Surgery on the affected knee within the last 6 months
- Previous total knee arthroplasty on the affected knee
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit
Duration - Duration of 4 sessions prior to surgery and encouragement to use skills post-surgery
Participants engage in 4 behavioral sessions either learning Savoring Meditation to generate positive emotional states or receiving Pain Self-Management and Education about chronic pain.
4 sessions with a trained interventionist
Duration - Up to 3 months post-surgery
Participants are followed for recovery and assessment of pain, opioid use, and functional outcomes after total knee arthroplasty.
Assessments at post-treatment, 6 weeks, and 3 months post-surgery
Trial Site Locations
Total: 1 location
1
Fontaine Research Park
Charlottesville, Virginia, United States, 22903
Actively Recruiting
Research Team
P
Patrick Finan, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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