Inclusion

• Age: 18 years or older
• Assigned male sex at birth
• Identifies as male at enrollment
• Report having engaged in condomless anal sex with another man in the past 3 months
• Report having exchanged sex for money, drugs, items of value, or a place to stay with another man in the past 3 months
• Report HIV status as negative or unsure
• Not currently on PrEP
• Able to understand and speak English or Spanish

Exclusion

• Unable to provide informed consent due to severe mental or physical illness, cognitive impairment, or substance intoxication at the time of interview (will use an adapted version of the Evaluation to Sign Consent Form65 to assess capacity)
• Discovery of active suicidal ideation or major mental illness (e.g. untreated psychosis or mania) at the time of interview (these patients will be referred immediately for treatment)
• Laboratory or clinical findings that would preclude PrEP initiation (e.g. Chronic Hepatitis B Virus infection, decreased creatinine clearance)
• Participated in the pilot RCT and initiated PrEP during study participation

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety