Actively Recruiting

Phase Not Applicable
Age: 50Years +
All Genders
NCT06998966

Optimizing Proton Pump Inhibitors (PPI) Prescribing With EHR-Based Decision Support

Led by University of California, Los Angeles · Updated on 2026-04-29

372

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

Sponsors

U

University of California, Los Angeles

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The proposed study is a quality improvement initiative designed to rigorously evaluate new variations of UCLA Health's proton pump inhibitor (PPI) order panels, building on internal quality improvement efforts to optimize prescribing workflows within the Electronic Health Record (EHR). PPIs are notoriously overprescribed, and the study team has identified that the CareConnect default prescription setting of 90 days with three refills (360 pill days) exceed standard guidelines (in most cases, 60 pill days). It is unclear whether this is the most appropriate workflow. Given that deprescribing PPIs carries minimal risk for most patients, this initiative will assess whether modifying defaulted prescription lengths influences prescribing behavior while ensuring physicians retain full decision-making authority. This evaluation of PPI order panel variations is embedded within UCLA's existing EHR system, ensuring that changes are tested pragmatically within routine workflows. The study aims to determine whether small adjustments to the order panel can better align prescribing patterns with clinical best practices while maintaining physician autonomy.

CONDITIONS

Official Title

Optimizing Proton Pump Inhibitors (PPI) Prescribing With EHR-Based Decision Support

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • UCLA Health primary care physicians who have a clinical full-time equivalency of at least 25%
Not Eligible

You will not qualify if you...

  • Physicians with a clinical full-time equivalency of less than 25%

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UCLA Health System

Los Angeles, California, United States, 90024

Actively Recruiting

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Research Team

K

Katelyn Clinical Research Coordinator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

3

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