Actively Recruiting

Age: 50Years - 70Years
All Genders
NCT05344573

Optimizing Pulsatility During Cardiopulmonary Bypass

Led by University of Colorado, Denver · Updated on 2024-11-21

66

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

Sponsors

U

University of Colorado, Denver

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Cardiopulmonary bypass during cardiac surgery provides blood flow to the body during surgery but has adverse effects on different organs. Blood flow during cardiopulmonary bypass may be pulsatile or non-pulsatile, which may impact normal organ function after surgery. The study will collect data on the type of cardiopulmonary bypass used during surgery and organ function to determine if there is an association between the type of bypass and organ function.

CONDITIONS

Official Title

Optimizing Pulsatility During Cardiopulmonary Bypass

Who Can Participate

Age: 50Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50 to 70 years
  • Able to provide informed consent
  • Scheduled for elective cardiac surgery with cardiopulmonary bypass
Not Eligible

You will not qualify if you...

  • Undergoing emergency procedures
  • Diagnosed with sepsis
  • Experiencing delirium
  • Experiencing hemodynamic instability (heart rate > 100 and systolic blood pressure < 90)
  • Having a mechanical circulatory support device
  • Requiring vasoactive medications before surgery
  • Reduced left ventricular ejection fraction (less than 50%)
  • Contraindication to transesophageal echocardiography

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Colorado Hospital

Aurora, Colorado, United States, 80045

Actively Recruiting

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Research Team

N

Nathan J Clendenen, MD, MS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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