Actively Recruiting
Optimizing Recruitment to Drive Equitable Research Opportunity in Stroke Rehabilitation Trials in Canada
Led by McMaster University · Updated on 2025-09-26
120
Participants Needed
5
Research Sites
106 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Stroke is a major health issue in Canada. Stroke affects over 400,000 Canadians, and this number is expected to nearly double by 2038. Research studies in stroke recovery can help us better understand effective rehabilitation treatments and help reduce the burden of stroke. Some groups of people however are commonly not included in stroke studies. For example, it is more common for men to take part in research than women, and people with aphasia (a language impairment commonly seen after stroke) are often excluded from studies. Also, deciding whether to even take part in a research study can be difficult and overwhelming, especially in the early days after stroke, leaving many people to decline to participate. Research has shown that women experience different barriers to participating in stroke research than men. This means that research findings, and the decisions made during stroke care based on these findings, may not reflect the true stroke population. Better ways to help support groups like women and people with aphasia to participate in stroke research are needed, so that study findings will better represent people living with stroke.
CONDITIONS
Official Title
Optimizing Recruitment to Drive Equitable Research Opportunity in Stroke Rehabilitation Trials in Canada
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Primary ischemic anterior circulation stroke
- Age 18 years or older
- Between 5 days and less than 8 weeks after stroke at medication start
- Hemiparesis requiring inpatient rehabilitation
- Assistance available for daily rehabilitation practice and transportation when needed
- Adequate language skills to understand informed consent and therapy information
- At least one of: some shoulder abduction with gravity eliminated and visible extension in two or more fingers OR visible hip flexion or extension
You will not qualify if you...
- Pre-stroke modified Rankin score of 2 or higher
- Limited resources or illness preventing return to living outside a facility
- History of dementia
- History of hepatitis or elevated liver enzymes
- History of kidney problems or low creatinine clearance
- Cancer or chronic illness limiting 1-year survival or ability to exercise
- Serious disabling diseases before stroke (e.g., Parkinson's, severe brain injury, amputation)
- Seizure related to stroke
- Acute or chronic epilepsy
- Currently taking Carbamazepine, Phenobarbital, or Phenytoin
- Pregnant, breastfeeding, or positive pregnancy test at baseline
- Women of childbearing potential not using effective contraception
- Known HIV positive
- Currently taking certain antifungal or antibacterial medications (Ketoconazole, Itraconazole, Voriconazole, Rifampin, Clarithromycin, Rifabutin with Protease Inhibitor)
- Currently taking St. John's Wort
AI-Screening
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Trial Site Locations
Total: 5 locations
1
University of Calgary & Foothills Medical Centre
Calgary, Alberta, Canada, T2N 2T9
Actively Recruiting
2
University of British Columbia & GF Strong Rehabilitation Centre
Vancouver, British Columbia, Canada, V5Z 2G9
Actively Recruiting
3
Dalhousie University
Halifax, Nova Scotia, Canada, B3H 3J5
Actively Recruiting
4
Parkwood Institute
London, Ontario, Canada, N6C 0A7
Actively Recruiting
5
Toronto Rehabilitation Institute - University Health Network
Toronto, Ontario, Canada, M5G 2A2
Not Yet Recruiting
Research Team
A
Ada Tang, PT PhD
CONTACT
H
Hanna Fang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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