Actively Recruiting
Optimizing a Sensor-Enabled mHealth Intervention for Adolescents With Suboptimal Asthma Control
Led by University of Kansas · Updated on 2025-12-24
160
Participants Needed
2
Research Sites
2 weeks
Total Duration
On this page
Sponsors
U
University of Kansas
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Asthma affects nearly one in ten teenagers in the United States and can significantly impact their health and daily life. Teens are expected to manage their asthma by taking medications correctly and monitoring symptoms, but this can be challenging as adolescents are still developing self-management skills and often receive less parental support. This trial evaluates a new system called Responsive Asthma Care for Teens (ReACT), designed to provide personalized, real-time support to help teens improve their asthma management skills. The study aims to test the feasibility and potential benefits of ReACT compared to a standard asthma education and symptom logging approach in teens with poorly controlled asthma. The study involves 160 teenagers aged 13 to 17 with suboptimal asthma control who will be randomly assigned to one of two groups for six months. One group will use the ReACT system, which includes a sensor to monitor medication adherence, training in problem-solving skills, ongoing tailored text messages with feedback and encouragement, and general asthma education. The other group will receive the standard mHealth care involving the same sensor monitoring and symptom reporting but only general asthma education without tailored support. Both groups will use smartphone apps to log symptoms and medication use. Participants will be involved in assessments at the start, at three months, and at six months, including surveys and objective data collection from the sensors. Researchers will measure recruitment feasibility, retention, engagement, acceptability, usability of the system, and burden on participants. They will also evaluate asthma control and quality of life using standardized tests. The study will help determine if ReACT and the study procedures are ready for a larger trial and provide early data on ReACT's impact on asthma outcomes for teens.
CONDITIONS
Brief Title
Optimizing a Sensor-Enabled mHealth Intervention for Adolescents With Suboptimal Asthma Control
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between 13 and 17 years old
- Physician-verified diagnosis of persistent asthma for at least 6 months
- Suboptimal asthma control as defined by national asthma guidelines
- Daily inhaled corticosteroid prescription compatible with the ReACT sensor
- Adolescent and caregiver speak and read English
You will not qualify if you...
- Currently involved in an asthma management intervention beyond usual care
- Comorbid chronic health condition affecting lung function (e.g., cystic fibrosis)
- Significant cognitive impairment or developmental delay interfering with study completion
- Does not have their own smartphone
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 months
Participants use a sensor to passively monitor adherence to their asthma regimen and report on their symptoms. Participants in the intervention arm receive tailored text messages with adherence feedback and problem-solving support, while participants in the control arm receive general asthma education.
Baseline visit and follow-up visits at 3 and 6 months
Trial Site Locations
Total: 2 locations
1
Nemours Children's Health
Jacksonville, Florida, United States, 32207
Actively Recruiting
2
University of Kanas
Lawrence, Kansas, United States, 66045
Actively Recruiting
Research Team
C
Christopher C. Cushing, Ph.D.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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