Actively Recruiting
Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults
Led by University of North Carolina, Chapel Hill · Updated on 2026-02-06
180
Participants Needed
1
Research Sites
176 weeks
Total Duration
On this page
Sponsors
U
University of North Carolina, Chapel Hill
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study seeks to answer the fundamental questions of which initial, first-line weight loss intervention should be offered to older adults with obesity and multiple chronic conditions and how to address the high non-response rates observed with most conventional strategies. A sequential, multiple assignment, randomized trial (SMART) design will permit the evaluation of treatment combinations that maximize weight loss and will provide data on constructing a future tailored, adaptive intervention. If successful, these findings will identify interventions that could markedly improve health and quality of life of these older adults, reduce long-term disability, and lower healthcare costs
CONDITIONS
Official Title
Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Community-dwelling adult living independently (not in nursing home or assisted living)
- Aged 65 to 85 years
- Obesity with body mass index of 30 kg/m2 or higher
- English-speaking
- Have two or more chronic medical conditions requiring ongoing care (excluding dementia and osteoporosis)
- Medical clearance from Primary Care Provider
- Callahan cognitive screen score of 3 or more correct items
- Older Americans Resources and Services survey score of 12 or higher
- Readiness to change score of 6 or higher out of 10
You will not qualify if you...
- Diagnosis of any type of dementia
- Previous weight loss surgery
- Untreated psychiatric disorder impairing participation (e.g., bipolar disorder, schizophrenia)
- Life-threatening illness
- Terminal illness with life expectancy less than 12 months
- Nursing home or hospital admission in past 3 months
- Advanced comorbidities
- Recent heart failure hospitalization or unstable heart disease
- Chronic kidney disease stage IV or V (GFR less than 30 ml/min)
- Active non-skin cancer treatment in past year
- Liver failure or cirrhosis
- COPD requiring oxygen or steroids
- Weight loss contraindication by Primary Care Provider
- Unstable weight loss greater than 5% in past 12 weeks
- Use of anti-obesity medications before study
- Use of certain bone-acting medications in past 1-2 years
- Osteoporosis or history of fragility fractures
- Elective surgery planned in next 12 months
- Recent COVID-19 infection within past month
- Participation in another weight loss study in past 12 months
- Planning to move away within next 18 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UNC Center for Aging and Health
Chapel Hill, North Carolina, United States, 27599
Actively Recruiting
Research Team
B
Brett R Sheppard, MA
CONTACT
J
John A Batsis, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
8
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