Actively Recruiting
Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients
Led by Rutgers, The State University of New Jersey · Updated on 2025-04-02
150
Participants Needed
1
Research Sites
76 weeks
Total Duration
On this page
Sponsors
R
Rutgers, The State University of New Jersey
Lead Sponsor
R
Rutgers Robert Wood Johnson Medical School
Collaborating Sponsor
AI-Summary
What this Trial Is About
Adult patients with morbid obesity who have had Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (LSG) surgery have impaired drug metabolism. There is a paucity of information available on how these patients metabolize acetaminophen post operatively and if drug preparation has any effect on achieving adequate pain control. The surgery may alter the stomach pH, reduce surface area of the stomach, affect transit time, and alter anatomic and physiologic standard absorption of medications. Due to these anatomic and physiologic changes, we seek to understand the potential effects of liquid versus pill formulations of acetaminophen on pain control in this patient population. The purpose of this study is to assess for subjective and objective measures of optimized pain control between formulations of acetaminophen including oral pills and oral liquid.
CONDITIONS
Official Title
Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years old or greater who meet patient selection criteria for either primary Roux-en-Y gastric bypass or primary laparoscopic sleeve gastrectomy.
You will not qualify if you...
- Known allergy or intolerance to acetaminophen or any inactive ingredients in either formulation.
- Patients unable or uncomfortable taking pills.
- Patients who had Duodenal Switch surgeries, Adjustable Gastric Banding, surgical revisions, or conversions.
- Patients with a history of chronic or current pain syndromes.
- Patients with opioid use disorder indicated by ICD-10 code F11.90.
- Vulnerable populations including children, prisoners, pregnant women, and mentally disabled persons.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Robert Wood Johnson University Hospital
New Brunswick, New Jersey, United States, 08690
Actively Recruiting
Research Team
D
Daniel T Abazia, PharmD
CONTACT
M
Mindy Rodden, PhD, RN, CPNP-AC
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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