Actively Recruiting

Early Phase 1
Age: 18Years +
All Genders
NCT07201714

Oral Carnitine in Heart Failure Patients

Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2026-04-20

20

Participants Needed

1

Research Sites

59 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Heart failure is a condition in which the heart is unable to pump blood effectively, leading to symptoms like being more tired, shortness of breath, and swelling in the body. Carnitine is a naturally occurring substance in the body that plays a role in turning fat into energy. This study will determine whether oral L-Carnitine supplementation can improve symptoms, enhance heart function and possibly improve the quality of life in individuals with heart failure.

CONDITIONS

Official Title

Oral Carnitine in Heart Failure Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical-pathological diagnosis of heart failure with some degree of cardiorenal syndrome
  • Stage 1, 2, 3a, 3b, or 4 chronic kidney disease
  • Age �3E�3D 18 years
  • Able to speak and read English
  • Willing and able to provide consent
Not Eligible

You will not qualify if you...

  • Estimated GFR <15 mL/min/1.73m2 or Stage 5 chronic kidney disease
  • Currently undergoing renal replacement therapy of any kind
  • Pregnant, breastfeeding or intending pregnancy
  • History of seizures of any type
  • Known allergy to levocarnitine, magnesium stearate, microcrystalline cellulose or povidone
  • Unable to provide consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

London Health Sciences Centre

London, Ontario, Canada, N6A 5W9

Actively Recruiting

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Research Team

K

Kathy Koyle

CONTACT

A

Amy Freeman, RN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

1

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