Actively Recruiting
Oral, Chemosensory and Trigeminal Functions in Allo-HSCT
Led by University of Oslo · Updated on 2026-05-01
70
Participants Needed
1
Research Sites
237 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this prospective, cohort study is to learn about smell, taste and trigeminal dysfunction in patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT). The research team hypothesizes that treatment with allo-HSCT will induce: * Distortion of taste and smell and trigeminal functions like cooling, tingling, and burning sensations. * Reduced saliva production leading to oral dryness and dental caries. * Changes in the connectivity of the taste-, smell- and pain-cortical brain regions.
CONDITIONS
Official Title
Oral, Chemosensory and Trigeminal Functions in Allo-HSCT
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients receiving myeloablative conditioning for a first-time allogeneic hematopoietic stem cell transplantation
- Diagnosis of leukemia or myelodysplastic syndrome
- Age between 30 and 70 years
You will not qualify if you...
- Disorders affecting the oral cavity including poor tooth status
- Use of drugs affecting gustatory or olfactory functions
- Presence of brain disorders
- Chronic disorders affecting the immune system
- Cancer other than leukemia or myelodysplastic syndrome
- Pregnancy
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Oslo
Oslo, Oslo, Norway, 0254
Actively Recruiting
Research Team
P
Per Ole Iversen, phd
CONTACT
M
Mahnoor Nazar, master
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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