Actively Recruiting

Phase 4
Age: 6Months - 24Months
All Genders
NCT05444699

Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age

Led by University of Oulu · Updated on 2025-02-13

210

Participants Needed

2

Research Sites

255 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the trial is to evaluate whether the use of oral prednisolone directed by point-of-care testing is useful in acute wheezing caused by rhinovirus in children aged 6-24 months.

CONDITIONS

Official Title

Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age

Who Can Participate

Age: 6Months - 24Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Wheezing bronchitis diagnosed by a physician
  • Need for salbutamol treatment at the emergency department
  • Positive nasopharyngeal rhinovirus or picornavirus finding in point-of-care testing
  • Age between 6 months and 24 months
Not Eligible

You will not qualify if you...

  • Need for immediate resuscitation
  • Immediate transfer to ICU
  • Suspected pneumonia based on auscultation
  • Suspected serious bacterial infection
  • Other respiratory virus findings without rhinovirus or picornavirus
  • Positive respiratory syncytial virus finding
  • Positive SARS-coronavirus-2 finding
  • Positive Mycoplasma pneumoniae finding
  • Positive Bordetella pertussis finding
  • Contact with chickenpox case within 14 days
  • Active chickenpox
  • Suspected foreign body in respiratory tract
  • Immunosuppressive treatment
  • Systemic corticosteroid treatment within 14 days
  • Allergy to corticosteroids

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

SOITE Lastenpäivystys

Kokkola, Finland

Actively Recruiting

2

OYS Lastenpäivystys

Oulu, Finland, 90130

Actively Recruiting

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Research Team

V

Ville Lindholm, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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