Actively Recruiting
Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis
Led by Peking University First Hospital · Updated on 2024-08-06
176
Participants Needed
1
Research Sites
154 weeks
Total Duration
On this page
Sponsors
P
Peking University First Hospital
Lead Sponsor
P
Peking University Third Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a multicenter randomized, placebo-controlled trial of Vitamin D supplementation in patients on peritoneal dialysis to determine whether oral administration of vitamin D3 after curing an episode of peritonitis could reduce the risk of subsequent peritoneal dialysis-related peritonitis.
CONDITIONS
Official Title
Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Medically stable and receiving peritoneal dialysis for > 1 month
- Older than 18 years old
- Serum 25(OH)D < 30ng/ml
- Adequate dialysis on evaluation with weekly Kt/V 1.5, or without clinical uremic symptoms
You will not qualify if you...
- Received Vitamin D2/D3 during the previous 1 month
- History of allergic reaction to Cholecalciferol
- Current or past malignant disease, active hepatitis or hepatic failure, active autoimmune disease, severe digestive malabsorption or an eating disorder, HIV/AIDS
- Acute systemic infection, cardiovascular disease, surgery, or trauma in the last month
- High probability of receiving a kidney transplant or transferring to hemodialysis or drop-out due to socioeconomic causes within 6 months
- History of kidney transplant
- Currently on hemodialysis combined with peritoneal dialysis
- Pregnant or breastfeeding
- Assessed by researchers as not suitable for enrollment, including patients who could not regularly follow-up
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Peking University First Hospital
Beijing, Beijing Municipality, China, 100034
Actively Recruiting
Research Team
J
Jie Dong, Professor
CONTACT
Z
Zhikai Yang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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