Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06228963

Orelabrutinib in the Treatment of HP-positive Gastric MALT Lymphoma

Led by Fudan University · Updated on 2024-02-23

160

Participants Needed

1

Research Sites

200 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Describe the efficacy and safety of Orelabrutinib in the treatment of HP-positive gastric MALT lymphoma

CONDITIONS

Official Title

Orelabrutinib in the Treatment of HP-positive Gastric MALT Lymphoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Histologically confirmed gastric mucosa-associated lymphoid tissue (MALT) lymphoma
  • Current infection with Helicobacter pylori confirmed by rapid urease test, histological staining, bacterial culture, urea breath test, or HpSA detection
  • ECOG performance status of 0 to 2
  • Lugano staging I to II1
  • Signed informed consent form
  • Presence of evaluable lesions
Not Eligible

You will not qualify if you...

  • Negative for Helicobacter pylori infection
  • History of other tumors except cured cervical cancer or basal cell carcinoma of the skin
  • Active HIV or syphilis infections
  • Pregnant or breastfeeding women
  • Severe active infections
  • Conditions affecting ability to take oral medication such as dysphagia, nausea, vomiting, chronic diarrhea, or intestinal obstruction
  • Other health conditions preventing completion of the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
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Trial Site Locations

Total: 1 location

1

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China, 200032

Actively Recruiting

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Research Team

Y

Yizhen Liu, M.D., Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Orelabrutinib in the Treatment of HP-positive Gastric MALT Lymphoma | DecenTrialz