Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT03064646

Organ Preservation in Locally Advanced Rectal Cancer

Led by Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · Updated on 2018-09-27

30

Participants Needed

1

Research Sites

516 weeks

Total Duration

On this page

Sponsors

F

Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana

Lead Sponsor

H

Hospital General Universitario Elche

Collaborating Sponsor

AI-Summary

What this Trial Is About

PRONAR trial aims to assess if treatment with organ preservation in stage II and III rectal cancer after a complete or almost complete response to neoadjuvant treatment is feasible and safe in our environment. The main objective of this project is to implement the organ preservation strategy in the treatment of rectal cancer in our environment within a clinical study that allows the analysis of its results in terms of survival. The secondary objective is to assess local relapse, distant relapse and quality of life.

CONDITIONS

Official Title

Organ Preservation in Locally Advanced Rectal Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with confirmed histopathological diagnosis of rectal adenocarcinoma.
  • Patients treated with neoadjuvant chemoradiotherapy or neoadjuvant radiotherapy associated or not with induction chemotherapy.
  • Patients with evidence of complete or near complete response criteria after completion of neoadjuvant treatment (approximately 8 weeks later). Response criteria should be based on digital rectal examination, flexible rectoscopy and MRI.
Not Eligible

You will not qualify if you...

  • Evidence of distant metastases.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Hospital General Universitario de Elche

Elche, Alicante, Spain, 03203

Actively Recruiting

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Research Team

J

Javier Gallego, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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