Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05397262

Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia

Led by University of Erlangen-Nürnberg Medical School · Updated on 2024-05-09

1000

Participants Needed

1

Research Sites

4318 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Analysis of the efficacy and the compatibility of deep regional hyperthermia in combination with radiotherapy and chemoradiotherapy in bladder cancer

CONDITIONS

Official Title

Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Histologically confirmed bladder cancer
  • No distant metastases (M0)
  • ECOG performance status of 2 or less
  • Provided informed consent to participate
Not Eligible

You will not qualify if you...

  • Uncontrolled cardiac disease, signs of heart failure, or rhythm problems needing treatment
  • Presence of a cardiac pacemaker
  • Heart attack within the past 12 months
  • Congestive heart failure
  • Complete bundle branch block
  • Severe heart disease classified as NYHA class III or IV
  • Conditions preventing TUR, chemoradiation, or deep regional hyperthermia
  • Metal implants longer than 2 cm or dense marker clips in the pelvic area
  • Active or treatment-resistant bladder infections
  • Existing or concurrent immunodeficiency syndrome
  • Pregnancy or breastfeeding
  • Not willing to use effective contraception during and up to 6 months after therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Dept. of Radiation Therapy, University Hospital Erlangen

Erlangen, Germany, 91054

Actively Recruiting

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Research Team

O

Oliver Ott, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia | DecenTrialz