Actively Recruiting

Phase Not Applicable
Age: 10Years - 35Years
All Genders
NCT07468019

Organization's Unique Protocol ID

Led by Cairo University · Updated on 2026-03-12

11

Participants Needed

1

Research Sites

43 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Ectodermal dysplasia is a rare inherited condition that affects structures derived from the ectoderm, including teeth, skin, hair, and sweat glands. Dental findings are often severe and include missing or malformed teeth and poorly developed jaw ridges. These abnormalities can significantly affect chewing, speech, facial appearance, and quality of life, especially in children and young adults. Removable dentures, particularly overdentures when some teeth are present, are commonly used to restore function and appearance in these patients because they are conservative and cost-effective. However, conventional acrylic dentures may show dimensional changes during processing, which can lead to poor denture fit, reduced retention, and lower patient satisfaction. Three-dimensional (3-D) printed dentures are a newer digital fabrication method that may reduce material shrinkage and improve denture adaptation. Despite these potential advantages, clinical evidence comparing 3-D printed and conventional overdentures in patients with ectodermal dysplasia remains limited, highlighting the need for well-designed clinical studies. The purpose of this study is to compare patient satisfaction and denture base adaptation between 3-D printed maxillary overdentures and conventional acrylic maxillary overdentures in patients with ectodermal dysplasia.

CONDITIONS

Official Title

Organization's Unique Protocol ID

Who Can Participate

Age: 10Years - 35Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age must range from 10-35 years.
  • Must have a few remaining teeth in the maxilla.
  • Must be willing to attend all follow-ups.
Not Eligible

You will not qualify if you...

  • Extreme anatomical limitations such as a large torus that requires surgical excision.
  • Allergy to dentures made of resins.
  • Pathological changes of residual ridges such as recurrent or persistent ulcers, osteomyelitis, and infections.
  • Medical or psychological conditions like physical disability or mental retardation that hinder cooperation in follow-up visits and answering questionnaires.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Dentistry, Cairo University

Cairo, Egypt

Actively Recruiting

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Research Team

Y

Yasmine Hisham Mohsen

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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