Actively Recruiting
Organization's Unique Protocol ID
Led by Cairo University · Updated on 2026-03-12
11
Participants Needed
1
Research Sites
43 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Ectodermal dysplasia is a rare inherited condition that affects structures derived from the ectoderm, including teeth, skin, hair, and sweat glands. Dental findings are often severe and include missing or malformed teeth and poorly developed jaw ridges. These abnormalities can significantly affect chewing, speech, facial appearance, and quality of life, especially in children and young adults. Removable dentures, particularly overdentures when some teeth are present, are commonly used to restore function and appearance in these patients because they are conservative and cost-effective. However, conventional acrylic dentures may show dimensional changes during processing, which can lead to poor denture fit, reduced retention, and lower patient satisfaction. Three-dimensional (3-D) printed dentures are a newer digital fabrication method that may reduce material shrinkage and improve denture adaptation. Despite these potential advantages, clinical evidence comparing 3-D printed and conventional overdentures in patients with ectodermal dysplasia remains limited, highlighting the need for well-designed clinical studies. The purpose of this study is to compare patient satisfaction and denture base adaptation between 3-D printed maxillary overdentures and conventional acrylic maxillary overdentures in patients with ectodermal dysplasia.
CONDITIONS
Official Title
Organization's Unique Protocol ID
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age must range from 10-35 years.
- Must have a few remaining teeth in the maxilla.
- Must be willing to attend all follow-ups.
You will not qualify if you...
- Extreme anatomical limitations such as a large torus that requires surgical excision.
- Allergy to dentures made of resins.
- Pathological changes of residual ridges such as recurrent or persistent ulcers, osteomyelitis, and infections.
- Medical or psychological conditions like physical disability or mental retardation that hinder cooperation in follow-up visits and answering questionnaires.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Faculty of Dentistry, Cairo University
Cairo, Egypt
Actively Recruiting
Research Team
Y
Yasmine Hisham Mohsen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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