Actively Recruiting
Oropharyngeal Candidiasis (OPC) and S-ECC
Led by Temple University · Updated on 2025-07-14
70
Participants Needed
1
Research Sites
191 weeks
Total Duration
On this page
Sponsors
T
Temple University
Lead Sponsor
C
Children's Hospital of Philadelphia
Collaborating Sponsor
AI-Summary
What this Trial Is About
The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of severe early childhood caries (S-ECC).
CONDITIONS
Official Title
Oropharyngeal Candidiasis (OPC) and S-ECC
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female individuals aged 9 to 24 months
- Must have at least one fully erupted tooth at baseline visit
- Parent or guardian willing and able to provide informed consent
- With or without a history of oropharyngeal candidiasis (OPC); 35 participants with and 35 without OPC history will be enrolled
You will not qualify if you...
- Presence of a systemic medical condition such as Down syndrome
- Presence of an orofacial deformity
- Presence of dental caries
- Use of systemic antimicrobial therapy within 30 days before the baseline visit
- Any condition that the investigator believes makes participation not in the individual's best interest
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Temple University
Philadelphia, Pennsylvania, United States, 19140
Actively Recruiting
Research Team
Y
Yuan Liu, DDS, MS, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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