Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07533240

Orthodontic and Articular Effects of the One-Step No-Prep Protocol

Led by Mainjot Amélie · Updated on 2026-04-16

30

Participants Needed

1

Research Sites

777 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study investigates how the One-Step No-Prep protocol with orthodontic assistance affects dental and jaw function in adults treated for localized tooth wear. It focuses on the predictability and extent of orthodontic tooth movements, the impact on temporomandibular joint position and function, and the quality and long-term stability of the restored bite. Participants will receive minimally invasive bonded restorations combined with simple orthodontic mechanics. The study will evaluate changes in tooth position, bite contacts, facial vertical height, and temporomandibular joint function using digital scans, low-dose 3D imaging, jaw-tracking, and clinical examinations. Patient comfort, function, and satisfaction will also be assessed through questionnaires. The goal is to better understand how this conservative treatment performs over time.

CONDITIONS

Official Title

Orthodontic and Articular Effects of the One-Step No-Prep Protocol

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Localized tooth wear that will be treated, or has already been treated, using the OSNPO protocol.
  • Age 18 years or older.
  • Sufficient cognitive ability to understand the study procedures and complete the required assessments.
  • Ability to read and complete the study questionnaires in French.
  • Written informed consent provided.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

University Hospital of Liège

Liège, Belgium, 4000

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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