Actively Recruiting

Phase Not Applicable
Age: 8Years - 15Years
All Genders
NCT06667037

Orthokeratology and 0.01% Atropine Sequential Treatment for Myopia Control

Led by Zhongshan Ophthalmic Center, Sun Yat-sen University · Updated on 2025-02-26

194

Participants Needed

1

Research Sites

131 weeks

Total Duration

On this page

Sponsors

Z

Zhongshan Ophthalmic Center, Sun Yat-sen University

Lead Sponsor

P

People's Hospital of Guangxi

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this multicenter randomized clinical trial is to evaluate the myopia control effect of orthokeratology and 0.01% atropine sequential treatment in children and adolescents, as compared to continuous treatment with orthokeratology.

CONDITIONS

Official Title

Orthokeratology and 0.01% Atropine Sequential Treatment for Myopia Control

Who Can Participate

Age: 8Years - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 8-15 years old.
  • Spherical equivalent refractions (SERs) between -0.50 and -6.00 Dioptres (D).
  • Astigmatism less than -1.5 D in both eyes.
  • Anisometropia less than 1.5 D.
  • Best corrected visual acuity (BCVA) equal to or better than 20/25 in both eyes.
  • Bilateral intra-ocular pressure less than 21 mmHg.
  • Normal binocular and stereoscopic visual function.
  • Participants and their guardians understand and accept random group assignment.
Not Eligible

You will not qualify if you...

  • Manifest strabismus, except for intermittent tropia.
  • Ocular or systemic diseases that may affect vision or refractive error.
  • Previous use of myopia control treatments without washout, including atropine, myopia control spectacles, or myopia control contact lenses.
  • Other contraindications.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zhongshan Ophthalmic Center Sun Yat-Sen University

Guangzhou, Guangdong, China, 510060

Actively Recruiting

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Research Team

Y

Yin Hu, Doctor

CONTACT

X

Xiao Yang, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Orthokeratology and 0.01% Atropine Sequential Treatment for Myopia Control | DecenTrialz