Actively Recruiting
OSNA Versus Ultrastaging to Detect Sentinel Lymph Node Metastasis in Endometrial Cancer
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-11-18
1922
Participants Needed
1
Research Sites
189 weeks
Total Duration
On this page
Sponsors
F
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead Sponsor
S
Sysmex Europe GmbH
Collaborating Sponsor
AI-Summary
What this Trial Is About
Patients enrolled in the study will be randomized before surgery: in one study arm, the search for lymph node metastases in surgically removed sentinel lymph nodes will occur using the ultrastaging method (standard), while in the other arm it will be conducted using the OSNA method.
CONDITIONS
Official Title
OSNA Versus Ultrastaging to Detect Sentinel Lymph Node Metastasis in Endometrial Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed endometrial cancer
- Apparent (pre-operative) FIGO stage I-II
- Candidates for radical surgery
- Planned attempt of sentinel lymph node mapping
You will not qualify if you...
- Uterine sarcoma including endometrial stromal sarcoma
- Fertility sparing surgery
- Dedifferentiated histology
- Undifferentiated histology
- Neoadjuvant therapy
- Previous surgery to pelvic lymph nodes
- Lymph nodes with short axis greater than 15 mm on pre-operative imaging
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rome, Italy, Italy, 00168
Actively Recruiting
Research Team
F
Francesco Fanfani, Professor
CONTACT
N
Nicolò Bizzarri, Dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here