Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06310278

Ossiview Normative Mobility Data Collection Protocol

Led by Audioptics Medical Incorporated · Updated on 2024-08-01

120

Participants Needed

1

Research Sites

25 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to learn about the sound-induced vibration level of certain structures in the middle ear in the normal-hearing population. The targeted structures are part of a chain of structures responsible for conducting sound within the auditory system and so their ability to vibrate normally in response to sound is relevant to the diagnosis of conductive hearing loss. The main questions the study aims to answer are: * What are the mean and variance of the normal sound-induced vibration level at two anatomical locations, the umbo of the malleus and the tip of the incus? * Are there any significant differences in these vibrational responses associated with sex or age? Participants will have their ossicular mobility measured with an investigational medical device that sends light into the middle ear and measures the motion-induced phase shift on light reflected from the target structures when a sound stimulus is presented. Standard hearing tests including audiometry and tympanometry will also be performed to confirm the normal hearing status of participants.

CONDITIONS

Official Title

Ossiview Normative Mobility Data Collection Protocol

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Normal hearing
  • Age 18 years or older
  • At least one of the incus or umbo visible during otoscopic examination
  • Type A 226Hz tympanogram with peak static compliance between -99mmH20 and +50mmH20
  • Peak static compliance range from 0.3 to 1.6 cc
Not Eligible

You will not qualify if you...

  • Audiometric air conduction thresholds above 40 dBHL at 500 Hz, 750 Hz, 1000 Hz, 1500 Hz, 2000 Hz, or 3000 Hz
  • Audiometric air-bone gap greater than 5 dB at 500 Hz, 750 Hz, 1000 Hz, 1500 Hz, 2000 Hz, or 3000 Hz
  • Ear infection within the past 3 months
  • Middle ear surgery in the last 5 years
  • Tympanic membrane perforation within the last 5 years
  • Medical treatment for any ear-related disorder within the last 5 years
  • Ear abnormalities found during otoscopy such as perforation, tympanosclerosis, otitis externa, thickened or fibrotic eardrum, mycosis, fluid, or infection

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Audioptics Medical

Halifax, Nova Scotia, Canada, B3H0A8

Actively Recruiting

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Research Team

R

Robert Adamson, PhD

CONTACT

C

Cathy Creaser, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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