Comparing Two Ostomy Closure Methods Using 0.1% BetainePolyhexanide Wound Irrigation Versus Pursestring Closure Effects on Surgical Site Infection and Healing in Adults

What this Trial Is About

Researchers are evaluating two different methods of closing ostomy wounds in patients ready for ostomy closure, focusing on surgical site infection rates, patient quality of life, and time to wound healing. The study compares primary ostomy closure after washing the wound with a 0.1% betaine and 0.1% polyhexanide antimicrobial solution Prontosan to the Pursestring closure method, where the wound is partially closed and allowed to heal from the inside out. This trial aims to find better treatment options for wound closure in colorectal surgery patients by comparing these approaches. Participants will be randomly assigned to one of two groups. One group will have their ostomy wound fully closed after irrigation with the Prontosan solution, involving a detailed suturing procedure. The other group will have their wound partially closed using the Pursestring technique, which leaves the wound open in the center to heal naturally. Both surgical procedures involve wound irrigation and specific closure techniques. The study will monitor outcomes for up to one year after surgery. During the study, participants will be monitored for signs of surgical site infection up to 30 days after surgery. Researchers will also assess wound healing time, patient perceptions of scar and wound healing, and the amount of wound care needed up to one year post-operation. Data will be collected on wound healing progress until complete closure, estimated around 4 to 6 weeks. The study includes various assessments to evaluate patient quality of life and wound outcomes over time.

Ostomy Primary Closure With 0.1% Betaine/Polyhexanide Wound Irrigation Compared to Pursestring Closure