Actively Recruiting
Clinical and Radiographic Outcome of Endodontic Retreatment in One or Two Visits: A Randomized Controlled Trial
Led by Universitat Internacional de Catalunya · Updated on 2020-08-26
110
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the success rate of non-surgical root canal retreatment performed in one visit compared to two visits in patients with periapical disease who require retreatment due to endodontic failure. This randomized controlled study aims to determine if there is any significant difference in treatment outcomes over a follow-up period of up to 10 years. The study is led by Universitat Internacional de Catalunya and focuses on endodontic diseases including root canal infection and endodontically treated teeth. Participants will receive non-surgical root canal retreatment either in a single visit or two separate visits. The study groups are randomized and treatment is administered by dental professionals following standardized procedures. The study monitors patients immediately after treatment and at several intervals up to 10 years to assess both clinical signs and radiographic evidence related to periapical disease. During the study, participants will be assessed for post-operative pain at various times: immediately, 4 hours, 24 hours, and 48 hours after treatment. Clinical symptoms and radiographic changes related to apical periodontitis will be evaluated at 1, 2, 4, 6, and 10 years. Researchers will also study correlations between prognostic factors and clinical outcomes. Safety and treatment success will be monitored over the long term, requiring participants to attend scheduled follow-up visits throughout the study period.
CONDITIONS
Brief Title
Outcome of Endodontic Retreatment in One or Two Visits
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who understand the study and willingly provide signed informed consent
- Willingness to comply with all study procedures and restrictions
- No clinically significant abnormalities in medical history or oral exam
- Cases of retreatment due to endodontic failure
- Diagnosis of apical periodontitis
- Single or bi-radicular teeth requiring retreatment
You will not qualify if you...
- Patients with systemic diseases, diabetes, immunocompromised status, or pregnancy
- Presence of clinically significant or relevant oral abnormalities
- Root resorption or root fractures
- Impossibility of restoration
- Cases where secondary root canal treatment is not the treatment of choice
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 to 2 visits
Participants receive non-surgical root canal retreatment, either in one or two visits depending on their assigned group.
1 to 2 visits (in-person)
Duration - Up to 10 years
Participants are monitored for clinical signs or symptoms of periapical disease and radiographic changes over several years after treatment.
Multiple visits for assessments at 1, 2, 4, 6, and 10 years post-treatment
Trial Site Locations
Total: 1 location
1
Universitat Internacional de Catalunya
Sant Cugat del Vallès, Barcelona, Spain, 08195
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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