Actively Recruiting

Age: 18Years +
All Genders
NCT06485622

Outcome and Improvement of Different Treatment in Arteriosclerosis Obliterans

Led by First Affiliated Hospital, Sun Yat-Sen University · Updated on 2025-08-08

400

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a prospective, single-center, observational study. In this study, we aim to evaluate the clinical outcome and cost-effectiveness of different treatments of lower extremity arterial occlusive disease. It is expected to include about 400 patients diagnosed with lower extremity arterial occlusive disease in our center from July 2024 to July 2026. All enrolled patients will be followed for three years. All patients diagnosed with arteriosclerosis obliterans (ASO) and all treatment techniques were included in this study. The primary outcomes include the Efficacy and Safety End Points of each techniques.

CONDITIONS

Official Title

Outcome and Improvement of Different Treatment in Arteriosclerosis Obliterans

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  1. Age 18 years or older, gender is not limited.
  2. Patients diagnosed with arteriosclerosis obliterans.
  3. Rutherford stages 2-6.
  4. When there are multiple stenosis lesions, the treatment of the most severe lesion is included.
  5. Patients with at least one arterial occlusion ( iliac, femoral, popliteal, anterior tibial, posterior tibial, and/or peroneal artery) of the lower extremity were included.
Not Eligible

You will not qualify if you...

  1. Malignant tumor
  2. Alzheimer's disease
  3. Blood disease or bleeding tendency
  4. Heart Failure Grade III ~ IV
  5. Pregnancy or lactation
  6. An above-knee-below-knee amputation has been performed
  7. Unable to accept therapeutic function tests
  8. Life expectancy is less than six months
  9. Combined with other diseases affecting walking
  10. Cardiovascular and cerebrovascular events occurred within 3 months, including non-fatal myocardial infarction, unstable angina, stable angina, non-fatal ischemic stroke and hemorrhagic stroke
  11. Patients with significant abnormal liver and renal function that the investigators judged to be clinically significant

AI-Screening

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Trial Site Locations

Total: 1 location

1

The First Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, China, 510030

Actively Recruiting

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Research Team

H

Haoliang Wu

CONTACT

Z

Zilun Li

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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