Actively Recruiting
Comparing Bipolar Enucleation and Transurethral Resection for Enlarged Prostate Treatment in Men A Multi-Center Randomized Trial on Outcomes, Patient Experiences, and Cost-Effectiveness
Led by Sykehuset Innlandet HF · Updated on 2026-05-01
120
Participants Needed
2
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating whether bipolar enucleation of the prostate BEEP leads to better urinary voiding outcomes than transurethral resection of the prostate TURP in men with enlarged prostates experiencing voiding problems. This multi-center randomized controlled trial focuses on men with prostate sizes between 30mL and 80mL who have lower urinary tract symptoms caused by benign prostate obstruction. The study also explores how symptom relief relates to the amount of tissue removed, differences in patient experiences between the two procedures, and the cost-effectiveness of BEEP compared to TURP. Participants will be randomly assigned to receive either TURP or BEEP, both transurethral surgical procedures performed to relieve urinary symptoms by removing prostate tissue. TURP involves removing central prostatic tissue starting from the bladder neck downwards, while BEEP removes tissue starting in the peripheral zone towards the bladder. Outcomes will be assessed at baseline and 12 months after surgery, with additional patient experience questionnaires at 3 and 12 months. Both procedures are performed under standard surgical care by experienced urologists. During the study, participants will complete the International Prostate Symptom Score IPSS to measure urinary symptoms and the Nordic Patients Experience Questionnaire NORPEQ to evaluate patient experience. Additional assessments include urinary flow measurements, residual urine volume, complications, catheter use, quality of life questionnaires, sexual function, and health care resource use. Cost-effectiveness will be analyzed using quality-adjusted life years QALYs over the 12-month follow-up. The study aims to enroll 120 men, with follow-up visits and data collection managed through electronic systems over one year.
CONDITIONS
Brief Title
Outcome and Patient Experiences After Transurethral Resection and Bipolar Enucleation of the Prostate - a Multi-center, Randomized Controlled Trial.
Research Team
O
Ola Christiansen, PhD
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