Comparing Outcomes and Quality of Life After Minimally Invasive and Open Esophagectomy

What this Trial Is About

Researchers are evaluating the short and long-term outcomes of minimally invasive esophagectomy MIE compared to open esophagectomy in patients undergoing surgery for esophageal cancer. They aim to measure both standard clinical results such as complications, mortality, and tumor recurrence, as well as patient-reported outcomes focused on quality of life QOL. The study also seeks to determine how well the MOS SF36 questionnaire reflects changes in patients health status before and after surgery, and to compare it with disease-specific measures of swallowing difficulties and reflux symptoms. Participants in this observational study complete quality of life and heartburn assessment questionnaires before surgery and at scheduled times after surgery. The study monitors changes in QOL at multiple time points, including 4, 6, 12, 18, 24, 30, and 36 months post-surgery. It also assesses the impact of additional treatments given before or after surgery on patient quality of life. Throughout the study, researchers collect and analyze questionnaire data to evaluate changes in patient well-being over time. The primary outcome is the change from baseline in the SF36 Quality of Life Questionnaire at each postoperative interval. Participants provide consent and complete the assessments as part of their involvement. The study continues to monitor these outcomes long term, with participation extending up to 36 months after surgery.

Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life